4 edition of Bacterial Protein Toxins (Zentralblatt Fur Bakteriologie, Supplement , Vol 28) found in the catalog.
Bacterial Protein Toxins (Zentralblatt Fur Bakteriologie, Supplement , Vol 28)
November 1996 by Vch Pub .
Written in English
|Contributions||Peer Lyng Frandsen (Editor), Joseph E. Alouf (Editor), Poul Falmagne (Editor), F. J. Fehrenbach (Editor), John H. Freer (Editor), C. Montecucco (Editor), Sjur Torkel Wadstrom (Editor)|
|The Physical Object|
|Number of Pages||377|
The toxin cause tetanus, a fatal disease that involves unfavorable muscle spasms that can cause respiratory failure and even death. This process inactivates protein synthesis in animal cellsresulting in cell death. Subsequent chapters provide information on computational approaches, and include a number of specific examples. Exotoxins are generated and actively secreted; endotoxins remain part of the bacteria. He is also the co-editor of several books. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes pore formation or stimulating cell receptors superantigens.
In both cases, a large protein molecule must insert into and cross a membrane lipid bilayer. Toxins that are phospholipases may be relatively nonspecific in their cytotoxicity because they cleave phospholipids which are components of host cell membranes resulting in the death of the cell by leakage of cellular contents. It is a hexameric protein comprising five distinct subunits, designated S1-S5. Pseudomonas aeruginosa toxins 6.
Subunit B allows the toxin to bind to the membrane of a target host cell. Fragment A, which is responsible for the catalytic activity of the toxin, is masked until it reaches the target cell. HC determines the cellular specificity with a protein receptor SV2 or Syt depending on the isoform and a ganglioside. References[ edit ] 1. Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes.
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In direct entry, the toxin binds to a target cell surface receptor. Doody's Review Service " Toxoids are the immunizing agents against diphtheria and tetanus that are part of the DPT vaccine.
He has published in major journals in toxinology, immunology and drug delivery. These secreted virulence factors assist the bacterium in surviving immune response mechanisms.
Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes.
Recent progress in bacterial genome mapping and establishment of three-dimensional crystal structures of several bacterial toxins provides a deeper knowledge and greater understanding of structure-function relationships. Endotoxins, which are structural components of bacteria, are cell-associated substances that a located in the cell envelope Bacterial Protein Toxins book can be released from growing bacteria or lysed cells as a consequence of effective host defense mechanisms or antibiotics.
Then, BoNTs enter the cells via receptor-mediated endocytosis, induces a conformational change and the light chains LCs cleave the unique components Bacterial Protein Toxins book the synaptic vesicle docking-fusion complex known as SNARE.
The final prices may differ from the prices shown due to specifics of VAT rules About this book In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein Bacterial Protein Toxins book.
Keywords aflatoxins bacterial protein cell-based fluorescent assays endotoxins mold fungus molecular methods toxicology Editors and affiliations. There is material here of value to most readers. He has been an active member of the International Society on Toxinology IST for 30 years and was president from to The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation.
Evidence to support this view comes from several lines. Audience: The intended audience not explicitly stated would include graduate students, research fellows, and those senior investigators interested in understanding the tools used in this area. Exotoxins are usually polypeptides that act at tissue sites remote from the original point of bacterial invasion or growth.
Perfringolysin O and related cholesterol-dependent cytolysins: mechanism of pore formation The body's response to an endotoxin can involve severe inflammation. Evolutionary aspects of toxin-producing bacteria 2.
Popoff, D. The latter could occur if the bacterium is too weak to prevent its destruction by the strong host defences it has incited or if its potent virulence wipes out the host and, thus, its source of food.PDF | On Sep 1,Cyril J.
Smyth and others published The Comprehensive Sourcebook of Bacterial Protein Toxins:The Comprehensive Sourcebook of Bacterial Protein Toxins | Find, read and cite Author: Cyril J Smyth. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors.
In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and. This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening).The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written pdf internationally known and well-respected galisend.com book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins.Microbial Toxins, A Comprehensive Treatise, Volume IIA: Bacterial Protein Toxins provides a comprehensive discussion of various aspects of bacterial toxins.Ebook Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected galisend.com book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins.